BOURNE - Three people sustained life-threatening injuries following a one-vehicle accident on Route 25 this afternoon, according to the state police.

A 1995 Ford Econoline van was traveling eastbound one mile from the Bourne Bridge when the driver lost control of the vehicle. It rolled over and came to rest in the median, ejecting two occupants and trapping the third inside the van, the state police said.

Of the two people ejected, one landed in the eastbound lane and the other on the westbound side of the highway. The victim inside the car had to be "freed by mechanical means," the state police said.

No other drivers were injured, police said.

All three men were seriously injured and taken to Toby and Falmouth hospitals. The police have no further word on their conditions.

Route 25 was closed for a time following the accident, but was partially reopened by 1:50 p.m. with the left lane closed in each direction. Area traffic was snarled.

The cause of the crash is under investigation by the state police, with assistance from the State Police Collision Analysis Reconstruction and the State Police Crime Scene Services teams.